The androgen sensitive meibomian glands may be altered in those taking…finasteride given its unique potency and targeted effects compared to other anti-androgenics.

[T]his represents the largest demographic study over 15 years of [dry eye disease] patients on finasteride, demonstrating an association with finasteride usage and [meibomian gland dysfunction], conjunctival, and corneal abnormalities. The androgen sensitive meibomian glands may be altered in those taking anti-androgen medications, and especially finasteride given its unique potency and targeted effects compared to other anti-androgenics. This study reinforces the importance of considering the long-term effects of finasteride use on DED as part of the systemic sequelae of androgen depletion and provides anticipatory guidance for patients and ophthalmologists.

—The effect of finasteride on dry eye disease, Investigative Ophthalmology & Visual Science: June 2022