The side effects of 5-ARI, related to the sexual sphere, mainly include erectile dysfunction and decreased libido and, less frequently, ejaculation disorders, decreased semen volume, decreased penis size, gynecomastia…muscle atrophy, fatigue, dry skin, cognitive disorders, depression, etc. are also reported… Post-finasteride syndrome is defined as the persistence of sexual, physical and psychological symptoms that appear with the use of the drug and that persist over time after stopping treatment… The persistence of these side effects causes anxiety, depression and alteration in their quality of life in patients. It is important to consider these side effects and inform the patient of the possibility of their appearance, and their possible persistence over time after stopping treatment.
—Post-finasteride syndrome, an entity to take into account in the treatment of patients with benign prostatic hyperplasia: LiveMed, July 7, 2022