Blocking 5 alpha-reductase to any degree in the brain is a crapshoot. Theoretically, you are going to block the production of hormones that serve very important behavioral purposes. Essentially, the cells get too much DHT, it puts them in overdrive and it burns them out. But unfortunately, in some men, the damage is hardwired.
—The Medical Mystery Behind America’s Best-Selling Hair-loss Drug: Tonic magazine, Nov. 21, 2016